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Healthcare · San Diego, CA

Registered Nurse Salary in San Diego, CA (2025)

Estimated pay for Registered Nurses working in San Diego, based on California salary adjusted for city cost of living.

Last updated: April 2025 · Source: BLS + Cost-of-Living Adjustment
$134,000
Annual in San Diego
$64.4/hr
Hourly Rate
$11,167
Monthly
$2,577
Weekly

San Diego vs California vs National

LocationAnnual Salaryvs. National
San Diego, CA$134,000+65%
California$112,000+20%
National Median$81,220baseline

City estimates use state salary adjusted by cost-of-living multiplier for San Diego.

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